Diabetes and Immunology

Type 1 diabetes is a chronic T-cell mediated disease that leads to the destruction of the insulin-secreting islet β-cells resulting in absolute insulin deficiency and hyperglycaemia. The clinical presentation of T1D is preceded by an asymptomatic period lasting from months to years which is characterised by autoantibodies against islet β-cell components. Insulin autoantibodies are amongst the first to appear, followed by autoantibodies to glutamic acid decarboxylase and then spreading to IA-2 (insulinoma-associated tyrosine phosphatase protein) and ZnT8 (zinc-transporter 8).

  • Islet cell auto-antigens
  • Immune cells
  • Therapies using immune modulators
  • Vaccination

Related Conference of Diabetes and Immunology

October 30- November 1, 2017

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Diabetes and Immunology Conference Speakers

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