Inflammation and Insulin Resistance

Inflammation plays a central role in the development of insulin resistance, a key factor in Type 2 Diabetes. Chronic low-grade inflammation, often triggered by factors like obesity, poor diet, and lack of exercise, can impair insulin signaling pathways and prevent cells from responding effectively to insulin. Inflammatory molecules, such as cytokines, interfere with glucose uptake in muscle and fat tissues, contributing to higher blood sugar levels. This creates a vicious cycle, where insulin resistance further promotes inflammation. Researchers are investigating anti-inflammatory strategies, including lifestyle changes, medications, and targeted therapies, to reduce inflammation and improve insulin sensitivity. By addressing inflammation, it may be possible to prevent or delay the onset of insulin resistance and Type 2 Diabetes.

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